Article In: cienciavitae, orcid, scopus

Compelling DNA intercalation through ‘anion–anion’ anti-coulombic interactions: boron cluster self-vehicles as promising anticancer agents

Journal of Materials Chemistry B

Gutiérrez-Gálvez L.; García-Mendiola T.; Viñas C. — 2024 — Royal Society of Chemistry (RSC)

Key information

Authors:

Gutiérrez-Gálvez L.; García-Mendiola T.; Lorenzo E.; Nuez-Martinez M.; Ocal C.; Yan S.; Teixidor F.; Pinheiro T. (Maria Teresa Ferreira Marques Pinheiro); Marques F. (Fernanda Marujo Marques); Viñas C.

Published in

August 7, 2024

Abstract

<jats:p>The amphiphilic anionic ferrabis(dicarbollide) boron-rich small molecule effectively penetrates the nucleus as a carrier-free drug and intercalates with ds-DNA base pairs, making it a promising candidate for multimodal cancer radiotherapy.</jats:p>

Publication details

Authors in the community:

Publication version

VoR - Version of Record

Publisher

Royal Society of Chemistry (RSC)

Title of the publication container

Journal of Materials Chemistry B

First page or article number

9550

Last page

9565

Volume

12

Issue

38

ISSN

2050-750X

DOI

10.1039/D4TB01177E

Fields of Science and Technology (FOS)

biological-sciences - Biological sciences

Publication language (ISO code)

eng - English

Alternative identifier (URI)

https://doi.org/10.1039/D4TB01177E

Rights type:

Only metadata available

Financing entity

Ministerio de Economía y Competitividad

Identifier for the funding entity: RED2022-134120-T