M

Maria Matilde Soares Duarte Marques

ist11938

Interesses científicos

Mechanisms of chemical carcinogenesis induced by environmental and therapeutic xenobiotics
Synthesis of covalent DNA and protein adducts, and characterization of their structural and conformational effects
Design, synthesis and biological evaluation of organic and organometallic compounds with potential therapeutic properties (e.g., selective estrogen receptor modulators – SERMS, anti-HIV agents)
Development/validation of analytical methodologies for the detection and quantitation of biomarkers of exposure to carcinogenic agents, with emphasis on HPLC/MS-MS

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