In situ architecture, function, and evolution of a contractile injection system

18/08/2017

<jats:title>Identification of a new injection system</jats:title> <jats:p> To interact with other cells, bacteria use contractile machines that function similarly to membrane-puncturing bacteriophages. The so-called type 6 secretion system (T6SS) functions from inside a bacterial cell. Böck <jats:italic>et al.</jats:italic> used modern electron microscopy methods and functional assays to resolve the structure and function of a T6SS in the cellular context. They identified three modules and showed large-scale structural changes upon firing. T6SSs are organized in multibarrel gun-like arrays and may contribute to the survival of bacteria inside their host. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6352" page="713" related-article-type="in-this-issue" vol="357" xlink:href="10.1126/science.aan7904">713</jats:related-article> </jats:p>

Autores da comunidade :

• 

  J

  João Miguel da Costa Medeiros

  ist156841

  Afiliações e fontes

  De: orcid

  ID: 37697608

VoR - Versão publicada

American Association for the Advancement of Science (AAAS)

Science

713

717

357

6352

0036-8075

10.1126/science.aan7904

biological-sciences - Ciências Biológicas

Palavras-chave

• Multidisciplinary

eng - Inglês