Article In: orcid

In situ architecture, function, and evolution of a contractile injection system

Science

Désirée Böck; João M. Medeiros; Martin Pilhofer — 2017 — American Association for the Advancement of Science (AAAS)

Key information

Authors:

Désirée Böck; João M. Medeiros (João Miguel da Costa Medeiros); Han-Fei Tsao; Thomas Penz; Gregor L. Weiss; Karin Aistleitner; Matthias Horn; Martin Pilhofer

Published in

08/18/2017

Abstract

<jats:title>Identification of a new injection system</jats:title> <jats:p> To interact with other cells, bacteria use contractile machines that function similarly to membrane-puncturing bacteriophages. The so-called type 6 secretion system (T6SS) functions from inside a bacterial cell. Böck <jats:italic>et al.</jats:italic> used modern electron microscopy methods and functional assays to resolve the structure and function of a T6SS in the cellular context. They identified three modules and showed large-scale structural changes upon firing. T6SSs are organized in multibarrel gun-like arrays and may contribute to the survival of bacteria inside their host. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6352" page="713" related-article-type="in-this-issue" vol="357" xlink:href="10.1126/science.aan7904">713</jats:related-article> </jats:p>

Publication details

Authors in the community:

Publication version

VoR - Version of Record

Publisher

American Association for the Advancement of Science (AAAS)

Title of the publication container

Science

First page or article number

713

Last page

717

Volume

357

Issue

6352

ISSN

0036-8075

DOI

10.1126/science.aan7904

Fields of Science and Technology (FOS)

biological-sciences - Biological sciences

Keywords

  • Multidisciplinary

Publication language (ISO code)

eng - English

Rights type:

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