Master's Thesis

Digital Twin Interfaces for ICU Decision Making

João Pedro Proença Ramos — 2025

Key information

Authors:

João Pedro Proença Ramos (João Pedro Proença Ramos)

Supervisors:

Miguel Leitão Bignolas Mira da Silva (Miguel Mira da Silva); Luís Miguel Velez Lapão

Published in

October 24, 2025

Abstract

The Intensive Care Unit (ICU) is a high-stakes environment, requiring a significant volume of data, which is necessary for guaranteeing the right decision contributes to the patient’s improvement in the long run. Minimizing potential human error and enhancing the ability to predict how the treatment is going to evolve are key aspects to improving this area of treatment. This dissertation proposes the creation and use of a Digital Twin (DT) interface for patients in the ICU with the goal of improving patient care and decision-making via predictive analytics and real-time data integration. This dissertation investigates how they might be able to help with issues in ICUs. With the purpose of identifying how DTs can be implemented in ICUs, a Systematic Literature Review (SLR) was conducted. Based on the results from the SLR, a proposed solution is described. The proposed information system uses Machine Learning (ML) and Retrieval-Augmented Generation (RAG) to simulate treatment alternatives and forecast results, and design and usability principles to enhance user experience. The system was implemented, tested and evaluated, using the Design Science Method. Three prototypes of the system were created and evaluated by medical specialists.

Publication details

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Fields of Science and Technology (FOS)

electrical-engineering-electronic-engineering-information-engineering - Electrical engineering, electronic engineering, information engineering

Publication language (ISO code)

eng - English

Rights type:

Embargo lifted

Date available:

September 10, 2026

Institution name

Instituto Superior Técnico