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Mário Rui Almeida dos Santos
M

Mário Rui Almeida dos Santos

ist151826

Research interests

  • The host-bacteria interaction, in particular the S. meliloti-Medicago and the Burkholderia-epithelial lung cells. The S. meliloti-Medicago interaction is considered a model system for the study of symbiotic biological nitrogen fixation, a very important biological process that has major ecological and agricultural importance. Despite the extensive knowledge on this symbiotic process, there are several mechanisms and molecular determinants used by the bacteria and the plant that are still not completely understood. The Burkholderia spp. represent highly versatile bacteria capable of colonising a wide range of ecological niches. Bcc bacteria are opportunistic pathogens that are able to infect immunocompromised patients, particularly in the airways of cystic fibrosis patients. So there is the need for the study of Bcc irulence factors that play determinant roles during the establishment of infection

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